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Published in 2021 at "Pharmaceutical Research"
DOI: 10.1007/s11095-021-03041-9
Abstract: Purpose Proper taste-masking formulation design is a critical issue for instant-dissolving tablets (IDTs). The purpose of this study is to use the electronic tongue to design the additives of the 3D printed IDTs to improve…
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Keywords:
taste masking;
electronic tongue;
formulation design;
design ... See more keywords
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Published in 2020 at "Chemistry and physics of lipids"
DOI: 10.1016/j.chemphyslip.2020.105031
Abstract: Pharmaceutical products often have drawbacks of unacceptable taste and palatability which makes it quite difficult for oral administration to some special populations like pediatrics and geriatrics. To curb this issue different approaches like coating, granulation,…
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Keywords:
taste;
pharmaceutical formulations;
taste palatability;
lipids taste ... See more keywords
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Published in 2020 at "Journal of Drug Delivery Science and Technology"
DOI: 10.1016/j.jddst.2020.102030
Abstract: Abstract Black seed oil (BSO) has several therapeutic benefits, mostly owing to its active ingredient thymoquinone (TQ). BSO’s unpleasant taste and unavailability of dosage form suitable for children nictitate the need for a new formulation.…
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Keywords:
seed;
taste masking;
black seed;
alginate beads ... See more keywords
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Published in 2018 at "Journal of pharmaceutical sciences"
DOI: 10.1016/j.xphs.2017.11.019
Abstract: Fast-dissolving oral films (FDFs) provide an alternative approach to increase consumer acceptance by advantage of rapid dissolution and administration without water. Usually, FDFs require taste-masking agents. However, inclusion of these excipients could make developing the…
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Keywords:
slfdfs;
fast dissolving;
oral films;
formulation ... See more keywords
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Published in 2022 at "Chemical communications"
DOI: 10.1039/d2cc00040g
Abstract: The synthesis of the first water-soluble 2,2'',4,4''-terphen[3]arene bearing sulphonatopropoxy moieties (STP3) and its effective alleviation of aversive responses to alkaloids in vitro and in vivo, via the formation of supramolecular complexes, have been described. Using…
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Keywords:
soluble terphen;
terphen arene;
water soluble;
taste masking ... See more keywords
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Published in 2019 at "Pharmaceutical Development and Technology"
DOI: 10.1080/10837450.2019.1687520
Abstract: Abstract The objective of the study was to mask the unpleasant taste of captopril (CPT). Taste masking was achieved by complexation of CPT with a basic ion exchange resin, Dowex® 66, using the batch method.…
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Keywords:
taste;
cpt;
ion exchange;
gustatory system ... See more keywords
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Published in 2020 at "Journal of Pharmacy and Pharmacology"
DOI: 10.1111/jphp.13245
Abstract: A child‐friendly taste‐masking strategy using solid lipid microsphere (SLM) has been proposed to obscure the undesirable taste of some water‐soluble drugs. In this study, the reversed lipid‐based nanoparticle (RLBN) technique was used to encapsulate a…
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Keywords:
taste;
child friendly;
water soluble;
taste masking ... See more keywords
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1
Published in 2022 at "AAPS PharmSciTech"
DOI: 10.1208/s12249-022-02219-7
Abstract: In this study, chloroquine resinates were prepared at a 1:1 (w:w) drug-to-resin ratio using the batch method with polacrilex (PC), sodium polystyrene sulfonate (SPS), and polacrilin potassium (PP) ion exchange resins (IER). The influence of…
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Keywords:
clp;
resin;
taste masking;
chloroquine ... See more keywords
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Published in 2022 at "AAPS PharmSciTech"
DOI: 10.1208/s12249-022-02227-7
Abstract: Palatability is one of the most critical characteristics of oral preparations. Therefore, the exploration of new techniques to mask the aversive taste of drugs is in continuous demand. In this study, we fabricated and characterized…
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Keywords:
drug;
palatability;
release;
microscopy ... See more keywords
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Published in 2022 at "AAPS PharmSciTech"
DOI: 10.1208/s12249-022-02484-6
Abstract: Azithromycin (AZI) is a commonly used antibiotic with extremely bitter taste that severely decreases the compliance of patients. Besides, the poor solubility of AZI in alkaline pH makes it difficult to be absorbed in the…
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Keywords:
taste;
coated pellets;
release;
taste masking ... See more keywords
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Published in 2023 at "AAPS PharmSciTech"
DOI: 10.1208/s12249-023-02520-z
Abstract: It is well-known that plenty of active pharmaceutical ingredients (API) inherently possess an unpleasant taste, which influences the acceptance of patients, especially children. Therefore, manufacturing taste-masked dosage forms has attracted a lot of attention. This…
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Keywords:
approaches application;
technologies approaches;
taste;
overview taste ... See more keywords