Zebrafish and medaka T1R (taste receptor type 1) proteins mediate highly sensitive recognition of l‐proline
Sign Up to like & getrecommendations! Published in 2023 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.13558
Abstract: In vertebrates, nutritional tastants, such as amino acids and sugars, are recognized by G‐protein‐coupled receptors of the taste receptor type 1 (T1R) family. Previous studies have shown that fish T1Rs are functionally distinct from mammalian… read more here.
Keywords: taste receptor; zebrafish medaka; highly sensitive; proline ... See more keywords
Current Progress in Understanding the Structure and Function of Sweet Taste Receptor
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Molecular Neuroscience"
DOI: 10.1007/s12031-020-01642-4
Abstract: The sweet taste receptor, which was identified approximately 20 years ago, mediates sweet taste recognition in humans and other vertebrates. With the development of genomics, metabonomics, structural biology, evolutionary biology, physiology, and neuroscience, as well as… read more here.
Keywords: taste; sweet taste; biology; taste receptor ... See more keywords
Taste perception and expression in stomach of bitter taste receptor tas2r38 in obese and lean subjects
Sign Up to like & getrecommendations! Published in 2021 at "Appetite"
DOI: 10.1016/j.appet.2021.105595
Abstract: Differences in taste perception have been related to eating behavior, nutritional status, and diseases. Recently, taste receptors have been identified in several extra-oral tissues, such as the gastrointestinal tract, where they seem to influence processes… read more here.
Keywords: taste; taste perception; expression; taste receptor ... See more keywords
Non-nutritive sweetener activation of the pig sweet taste receptor T1R2-T1R3 in vitro mirrors sweetener stimulation of the gut-expressed receptor in vivo.
Sign Up to like & getrecommendations! Published in 2021 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2021.01.032
Abstract: The perception of sweet is mediated by the sweet taste receptor T1R2-T1R3 expressed in taste cells of the lingual epithelium. This receptor is also expressed in intestinal enteroendocrine cells and is required for sensing luminal… read more here.
Keywords: receptor; taste; t1r2 t1r3; taste receptor ... See more keywords
The taste of neuroinflammation: molecular mechanisms linking taste sensing to neuroinflammatory responses.
Sign Up to like & getrecommendations! Published in 2021 at "Pharmacological research"
DOI: 10.1016/j.phrs.2021.105557
Abstract: Evidence indicates a critical role of neuroinflammatory response as an underlying pathophysiological process in several central nervous system disorders, including neurodegenerative diseases. However, the molecular mechanisms that trigger neuroinflammatory processes are not fully known. The… read more here.
Keywords: taste; neuroinflammatory responses; taste receptor; molecular mechanisms ... See more keywords
Sweet Taste Receptor T1R3 Expressed in Leydig Cells Is Closely Related to Homeostasis of the Steroid Hormone Metabolism Profile.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.3c01110
Abstract: Taste receptor type 1 subunit 3 (T1R3) is initially expressed in mammal tongue for recognition and response of sweet/umami tastants and is critical to nutrient absorption, even endocrine. In this study, down-regulation of related steroidogenic… read more here.
Keywords: leydig cells; t1r3; taste receptor; testosterone ... See more keywords
Ultrasensitive Bioelectronic Tongue Based on the Venus Flytrap Domain of a Human Sweet Taste Receptor.
Sign Up to like & getrecommendations! Published in 2022 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.1c17349
Abstract: Sweet taste is an important factor that regulates calorie intake and contributes to food preferences in humans and animals. Therefore, the evaluation of sweet substances is essential for various fields such as healthcare, food, and… read more here.
Keywords: taste receptor; bioelectronic tongue; taste; sweet taste ... See more keywords
Massive Expansion of Bitter Taste Receptors in Blind Cavefish, Astyanax mexicanus
Sign Up to like & getrecommendations! Published in 2019 at "Chemical Senses"
DOI: 10.1093/chemse/bjy062
Abstract: A sensory deficit both at the individual and at the species level can be compensated by increased acuity in other senses. The loss of vision in blind cavefish, Astyanax mexicanus, appears to be partially counterbalanced… read more here.
Keywords: taste; blind cavefish; repertoire; taste receptor ... See more keywords
Conserved Residues Control the T1R3-Specific Allosteric Signaling Pathway of the Mammalian Sweet-Taste Receptor.
Sign Up to like & getrecommendations! Published in 2019 at "Chemical senses"
DOI: 10.1093/chemse/bjz015
Abstract: Mammalian sensory systems detect sweet taste through the activation of a single heteromeric T1R2/T1R3 receptor belonging to class C G-protein-coupled receptors. Allosteric ligands are known to interact within the transmembrane domain, yet a complete view… read more here.
Keywords: taste receptor; sweet taste; allosteric signaling; conserved residues ... See more keywords
Taste receptor polymorphisms and male infertility
Sign Up to like & getrecommendations! Published in 2017 at "Human Reproduction"
DOI: 10.1093/humrep/dex305
Abstract: STUDY QUESTION Are polymorphisms of taste receptor genes associated with male infertility? SUMMARY ANSWER This study has showed the associations between three single nucleotide polymorphisms (SNPs) in taste receptors genes (TASR) and male infertility. WHAT… read more here.
Keywords: taste; expression; male infertility; taste receptor ... See more keywords
PSVI-7 Variation in bitter taste receptor genes in three breeds of goats
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Animal Science"
DOI: 10.1093/jas/skz258.424
Abstract: The objective of this study was to detect bitter taste receptor (T2Rs) variants in three breeds of goats. The ability to taste bitter taste impacts feed intake, digestion, and rejection of potentially toxic substances. Blood… read more here.
Keywords: taste; three breeds; taste receptor; bitter taste ... See more keywords