Arf6-mediated macropinocytosis-enhanced suicide gene therapy of C16TAB-condensed Tat/pDNA nanoparticles in ovarian cancer.
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DOI: 10.1039/d1nr03974a
Abstract: The use of cell-penetrating peptides (CPPs), typically HIV-Tat, to deliver therapeutic genes for cancer treatment is hampered by the inefficient delivery and complicated uptake route of plasmid DNA (pDNA). On the one hand, surface charges,… read more here.
Keywords: suicide gene; gene therapy; tat pdna; cancer ... See more keywords