In Situ Tissue Labeling of Cerebral Amyloid Using HIV-Related Tat Peptide
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Neurobiology"
DOI: 10.1007/s12035-018-0870-x
Abstract: Delivering peptide-based drugs to the brain is a major challenge because of the existence of the blood-brain barrier (BBB). To overcome this problem, cell-penetrating peptides derived from proteins that are able to cross biological membranes… read more here.
Keywords: peptide; amyloid deposits; tissue; tat peptide ... See more keywords
Genetic transformation of Chlorella vulgaris mediated by HIV-TAT peptide
Sign Up to like & getrecommendations! Published in 2019 at "3 Biotech"
DOI: 10.1007/s13205-019-1671-2
Abstract: Scientific interest in microalgal species is growing and, genetic transformation has definitely opened more avenues, in the ongoing research on microphytes. In the present study, we have attempted to transform Chlorella vulgaris by mobilizing double-stranded… read more here.
Keywords: genetic transformation; chlorella vulgaris; vulgaris; transformation ... See more keywords
Nucleus-targeting near-infrared nanoparticles based on TAT peptide-conjugated IR780 for photo-chemotherapy of breast cancer
Sign Up to like & getrecommendations! Published in 2020 at "Chemical Engineering Journal"
DOI: 10.1016/j.cej.2019.122458
Abstract: Abstract Breast cancer is the most common malignant tumor in women. Phototherapy, mainly including photothermal therapy (PTT) and photodynamic therapy (PDT), shows many advantages such as high spatial selectivity, noninvasive nature, and negligible drug resistance… read more here.
Keywords: chemotherapy; cancer; breast cancer; nucleus targeting ... See more keywords
Closing the Loop: Constraining TAT Peptide by γPNA Hairpin for Enhanced Cellular Delivery of Biomolecules.
Sign Up to like & getrecommendations! Published in 2018 at "Bioconjugate chemistry"
DOI: 10.1021/acs.bioconjchem.8b00495
Abstract: Based on the exceptionally high stability of γPNA duplexes, we designed a peptide/γPNA chimera in which a cell-penetrating TAT peptide is flanked by two short complementary γPNA segments. Intramolecular hybridization of the γPNA segments results… read more here.
Keywords: tat peptide; pna hairpin; peptide pna; pna ... See more keywords
Inhibition of highly pathogenic avian influenza (HPAI) virus by a peptide derived from vFLIP through its direct destabilization of viruses
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-04777-4
Abstract: The antiviral activities of synthesized Kα2-helix peptide, which was derived from the viral FLICE-like inhibitor protein (vFLIP) of Kaposi’s sarcoma-associated herpesvirus (KSHV), against influenza A virus (IAV) were investigated in vitro and in vivo, and… read more here.
Keywords: peptide; peptide derived; highly pathogenic; influenza ... See more keywords
Effect of TAT-DOX-PEG irradiated gold nanoparticles conjugates on human osteosarcoma cells
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-63245-8
Abstract: The paper aims to investigate the cytotoxic effect on tumor cells of irradiated AuNPs in green light and subsequently functionalized with HS-PEG-NH 2 . The toxicity level of gold conjugates after their functionalization with DOX… read more here.
Keywords: dox tat; effect tat; dox; tat peptide ... See more keywords
State-of-the-art tools to elucidate the therapeutic potential of TAT-peptide (TP) conjugated repurposing drug against SARS-CoV-2 spike glycoproteins.
Sign Up to like & getrecommendations! Published in 2022 at "Current pharmaceutical design"
DOI: 10.2174/1381612829666221019144259
Abstract: BACKGROUND In late 2019, a highly infectious and pathogenic coronavirus was recognized as Severe Acute Respiratory Coronavirus 2 (SARS-CoV-2) which causes acute respiratory disease, threatening human health and public safety. A total of 448,327,303 documented… read more here.
Keywords: cov spike; drug; tat peptide; sars cov ... See more keywords
Examining the Cellular Transport Pathway of Fusogenic Quantum Dots Conjugated With Tat Peptide
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2022.831379
Abstract: Understanding the underlying transport mechanism of biological delivery is important for developing delivery technologies for pharmaceuticals, imaging agents, and nanomaterials. Recently reported by our group, SDots are a novel class of nanoparticle delivery systems with… read more here.
Keywords: tat peptide; transport; cellular transport; pathway ... See more keywords
A CRISPR-Cas and Tat Peptide with Fluorescent RNA Aptamer System for Signal Amplification in RNA Imaging
Sign Up to like & getrecommendations! Published in 2023 at "Biosensors"
DOI: 10.3390/bios13020293
Abstract: We reported on an efficient RNA imaging strategy based on a CRISPR-Cas and Tat peptide with a fluorescent RNA aptamer (TRAP-tag). Using modified CRISPR-Cas RNA hairpin binding proteins fused with a Tat peptide array that… read more here.
Keywords: peptide fluorescent; rna imaging; rna; cas tat ... See more keywords