Hyperphosphorylated Human Tau Accumulates at the Synapse, Localizing on Synaptic Mitochondrial Outer Membranes and Disrupting Respiration in a Mouse Model of Tauopathy
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DOI: 10.3389/fnmol.2022.852368
Abstract: Neurogenerative disorders, such as Alzheimer’s disease (AD), represent a growing public health challenge in aging societies. Tauopathies, a subset of neurodegenerative disorders that includes AD, are characterized by accumulation of fibrillar and hyperphosphorylated forms of… read more here.
Keywords: synaptic mitochondrial; tau; tau accumulates; hyperphosphorylated human ... See more keywords