Nitrosylation of GAPDH augments pathological tau acetylation upon exposure to amyloid-β
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DOI: 10.1126/scisignal.aao6765
Abstract: Blocking the nitrosylation of GAPDH may reduce amyloid-induced tau toxicity in the brain and slow the progression of Alzheimer’s disease. Nitrosylation links amyloid and tau pathology Amyloid-β (Aβ), tau aggregates, and nitrosative stress all contribute… read more here.
Keywords: nitrosylation; tau acetylation; gapdh; pathology ... See more keywords