Non-Amyloid PET Imaging Biomarkers for Neurodegeneration: Focus on Tau, Alpha-Synuclein and Neuroinflammation.
Sign Up to like & getrecommendations! Published in 2017 at "Current Alzheimer research"
DOI: 10.2174/1567205013666160620111408
Abstract: Clinical classifications of neurodegenerative disorders are often based on neuropathology. The term "proteinopathies" includes disorders that have in common abnormal proteins as a hallmark, e.g. amyloidoses, tauopathies, synucleopathies, ubiquitinopathies. Different proteins can also co-exist in… read more here.
Keywords: pet tracers; tau alpha; pet; non amyloid ... See more keywords
Tau and Alpha Synuclein Synergistic Effect in Neurodegenerative Diseases: When the Periphery Is the Core
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms21145030
Abstract: In neuronal cells, tau is a microtubule-associated protein placed in axons and alpha synuclein is enriched at presynaptic terminals. They display a propensity to form pathologic aggregates, which are considered the underlying cause of Alzheimer’s… read more here.
Keywords: tau alpha; synuclein synergistic; synuclein peripheral; peripheral tissues ... See more keywords