UBE4B, a microRNA-9 target gene, promotes autophagy-mediated Tau degradation
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DOI: 10.1038/s41467-021-23597-9
Abstract: The formation of hyperphosphorylated intracellular Tau tangles in the brain is a hallmark of Alzheimer’s disease (AD). Tau hyperphosphorylation destabilizes microtubules, promoting neurodegeneration in AD patients. To identify suppressors of tau-mediated AD, we perform a… read more here.
Keywords: degradation; overexpression; tau; tau degradation ... See more keywords