To target Tau pathologies, we must embrace and reconstruct their complexities
Sign Up to like & getrecommendations! Published in 2021 at "Neurobiology of Disease"
DOI: 10.1016/j.nbd.2021.105536
Abstract: The accumulation of hyperphosphorylated fibrillar Tau aggregates in the brain is one of the defining hallmarks of Alzheimer's disease (AD) and other Tauopathies. However, the primary events or molecules responsible for triggering Tau aggregation and… read more here.
Keywords: tau aggregation; tau; aggregation pathology; pathology ... See more keywords
Roles of Microglial and Monocyte Chemokines and Their Receptors in Regulating Alzheimer's Disease-Associated Amyloid-β and Tau Pathologies
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Neurology"
DOI: 10.3389/fneur.2018.00549
Abstract: Chemokines and their receptors have been shown to affect amyloid-β (Aβ) and tau pathologies in mouse models of Alzheimer's disease (AD) by regulating microglia and monocyte-associated neuroinflammation, microglial movement and monocyte recruitment into the brain.… read more here.
Keywords: amyloid tau; disease; chemokines receptors; tau pathologies ... See more keywords