Caspase‐6‐cleaved tau is relevant in Alzheimer's disease and marginal in four‐repeat tauopathies: Diagnostic and therapeutic implications
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DOI: 10.1111/nan.12819
Abstract: Tau truncation (tr‐tau) by active caspase‐6 (aCasp‐6) generates tau fragments that may be toxic. Yet the relationship between aCasp‐6, different forms of tr‐tau and hyperphosphorylated tau (p‐tau) accumulation in human brains with Alzheimer's disease (AD)… read more here.
Keywords: relevant alzheimer; disease marginal; cleaved tau; alzheimer disease ... See more keywords