Comparing Plasma Phospho Tau, Total Tau, and Phospho Tau–Total Tau Ratio as Acute and Chronic Traumatic Brain Injury Biomarkers
Sign Up to like & getrecommendations! Published in 2017 at "JAMA Neurology"
DOI: 10.1001/jamaneurol.2017.0655
Abstract: Importance Annually in the United States, at least 3.5 million people seek medical attention for traumatic brain injury (TBI). The development of therapies for TBI is limited by the absence of diagnostic and prognostic biomarkers.… read more here.
Keywords: tau; tau tau; tau total; tbi ... See more keywords
CSF p-tau increase in response to Aβ-type and Danish-type cerebral amyloidosis and in the absence of neurofibrillary tangles
Sign Up to like & getrecommendations! Published in 2021 at "Acta Neuropathologica"
DOI: 10.1007/s00401-021-02400-5
Abstract: Phosphorylated tau (p-tau) species in bodily fluids are among the most reliable molecular biomarkers for differential diagnosis and progression monitoring of Alzheimer’s disease (AD) [3]. The ATN research framework stages AD patients based on three… read more here.
Keywords: tau; p181tau; increase; tau tau ... See more keywords
Cerebrospinal fluid markers analysis in the differential diagnosis of dementia with Lewy bodies and Parkinson’s disease dementia
Sign Up to like & getrecommendations! Published in 2018 at "European Archives of Psychiatry and Clinical Neuroscience"
DOI: 10.1007/s00406-018-0928-9
Abstract: Dementia with Lewy bodies (DLB) and Parkinson’s disease dementia (PDD) share a couple of clinical similarities that is often a source of diagnostic pitfalls. We evaluated the discriminatory potential of brain-derived CSF markers [tau, p-tau… read more here.
Keywords: lewy bodies; dementia lewy; dementia; tau tau ... See more keywords
Tau protein in cerebrospinal fluid: a novel biomarker of the time of death?
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Legal Medicine"
DOI: 10.1007/s00414-021-02558-3
Abstract: Tau proteins are recognized biomarkers of neurodegeneration and neuronal damage in the cerebrospinal fluid (CSF). It has also been suggested that these CSF proteins could increase post-mortem due to neuronal death. The aim of this… read more here.
Keywords: death; tau; tau tau; time ... See more keywords
Changes of cerebrospinal fluid Aβ42, t-tau, and p-tau in Parkinson’s disease patients with cognitive impairment relative to those with normal cognition: a meta-analysis
Sign Up to like & getrecommendations! Published in 2017 at "Neurological Sciences"
DOI: 10.1007/s10072-017-3088-1
Abstract: The cerebrospinal fluid (CSF) signature of reduced amyloid beta 1–42 (Aβ42), elevated total tau (t-tau), and phosphorylated tau181 (p-tau) is important for the early diagnosis of Alzheimer’s disease (AD). Aβ42, t-tau, and p-tau have been… read more here.
Keywords: tau; tau tau; disease; cognitive impairment ... See more keywords
arXiv : Deep learning approach to the Higgs boson CP measurement in H to tau tau decay and associated systematics
Sign Up to like & getrecommendations! Published in 2017 at "Physical Review D"
DOI: 10.1103/physrevd.96.073002
Abstract: The H to tau tau decays form the prime channel for the measurement of the Higgs boson state and tests of the CP invariance of Higgs boson couplings. A previous study has shown the viability… read more here.
Keywords: higgs boson; tau; tau tau; deep learning ... See more keywords
RD(*) motivated S1 leptoquark scenarios: Impact of interference on the exclusion limits from LHC data
Sign Up to like & getrecommendations! Published in 2019 at "Physical Review D"
DOI: 10.1103/physrevd.99.055028
Abstract: Motivated by the persistent anomalies in the semileptonic $B$-meson decays, we investigate the competency of LHC data to constrain the $R_{D^{(*)}}$-favoured parameter space in a charge $-1/3$ scalar leptoquark ($\mathcal S_1$) model. We consider some… read more here.
Keywords: exclusion; exclusion limits; tau; motivated leptoquark ... See more keywords
Astrocytic tau pathologies in aged human brain
Sign Up to like & getrecommendations! Published in 2019 at "Neuropathology"
DOI: 10.1111/neup.12544
Abstract: Argyrophilic and tau‐positive abnormal structures in astrocytes are frequent in aged brains, with a new nomenclature of aging‐related tau astrogliopathy (ARTAG) proposed. The two major cytomorphologies of ARTAG are thorn‐shaped astrocytes (TSA) and granular or… read more here.
Keywords: tau positive; tau; tau tau; tau negative ... See more keywords
Mild traumatic brain injury is associated with increased levels of axonal injury biomarkers in blood
Sign Up to like & getrecommendations! Published in 2017 at "British Journal of Sports Medicine"
DOI: 10.1136/bjsports-2016-097270.15
Abstract: Objective To investigate whether sports-related concussion is associated with elevated blood biomarkers reflecting axonal injury (total-tau [T-tau], [tau-A] and [tau-C]) and astroglial injury (S100B), as well as neurons-specific enolase (NSE). Design and setting A multicenter… read more here.
Keywords: tau tau; axonal injury; concussion; sports related ... See more keywords
Alzheimer’s disease brain contains tau fractions with differential prion-like activities
Sign Up to like & getrecommendations! Published in 2021 at "Acta Neuropathologica Communications"
DOI: 10.1186/s40478-021-01127-4
Abstract: Neurofibrillary tangles (NFTs) made of abnormally hyperphosphorylated tau are a hallmark of Alzheimer’s disease (AD) and related tauopathies. Regional distribution of NFTs is associated with the progression of the disease and has been proposed to… read more here.
Keywords: tau; prion like; tau tau; disease ... See more keywords
Neurogranin, a synaptic protein, is associated with memory independent of Alzheimer biomarkers
Sign Up to like & getrecommendations! Published in 2017 at "Neurology"
DOI: 10.1212/wnl.0000000000004569
Abstract: Objective: To determine the association between synaptic functioning as measured via neurogranin in CSF and cognition relative to established Alzheimer disease (AD) biomarkers in neurologically healthy older adults. Methods: We analyzed CSF concentrations of neurogranin,… read more here.
Keywords: tau tau; delayed recall; memory; csf ... See more keywords