Integrated biology approach reveals molecular and pathological interactions among Alzheimer’s Aβ42, Tau, TREM2, and TYROBP in Drosophila models
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DOI: 10.1186/s13073-018-0530-9
Abstract: BackgroundCerebral amyloidosis, neuroinflammation, and tauopathy are key features of Alzheimer’s disease (AD), but interactions among these features remain poorly understood. Our previous multiscale molecular network models of AD revealed TYROBP as a key driver of… read more here.
Keywords: pathological interactions; molecular pathological; biology; tau trem2 ... See more keywords