Biomarkers of neuronal injury and amyloid metabolism in the cerebrospinal fluid of patients infected with HIV-1 subtypes B and C
Sign Up to like & getrecommendations! Published in 2017 at "Journal of NeuroVirology"
DOI: 10.1007/s13365-017-0591-3
Abstract: Based on prior reports that the HIV-1 Tat protein modulates amyloid-beta (Aβ) metabolism, this study aimed to compare CSF neural injury biomarkers between 27 patients with HIV subtype B, 26 patients with HIV subtype C,… read more here.
Keywords: tau; tau181; metabolism; hiv ... See more keywords
Blood phosphorylated tau 181 as a biomarker for Alzheimer's disease: a diagnostic performance and prediction modelling study using data from four prospective cohorts
Sign Up to like & getrecommendations! Published in 2020 at "The Lancet Neurology"
DOI: 10.1016/s1474-4422(20)30071-5
Abstract: BACKGROUND CSF and PET biomarkers of amyloid β and tau accurately detect Alzheimer's disease pathology, but the invasiveness, high cost, and poor availability of these detection methods restrict their widespread use as clinical diagnostic tools.… read more here.
Keywords: blood; tau181; cohort; alzheimer disease ... See more keywords
Plasma phosphorylated tau 217 and phosphorylated tau 181 as biomarkers in Alzheimer's disease and frontotemporal lobar degeneration: a retrospective diagnostic performance study
Sign Up to like & getrecommendations! Published in 2021 at "The Lancet Neurology"
DOI: 10.1016/s1474-4422(21)00214-3
Abstract: BACKGROUND Plasma tau phosphorylated at threonine 217 (p-tau217) and plasma tau phosphorylated at threonine 181 (p-tau181) are associated with Alzheimer's disease tau pathology. We compared the diagnostic value of both biomarkers in cognitively unimpaired participants… read more here.
Keywords: tau181; tau; pathology; tau217 ... See more keywords
Plasma phospho-tau181 in presymptomatic and symptomatic familial Alzheimer’s disease: a longitudinal cohort study
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Psychiatry"
DOI: 10.1038/s41380-020-0838-x
Abstract: Blood biomarkers have great potential to advance clinical care and accelerate trials in Alzheimer’s disease (AD). Plasma phospho-tau181 (p-tau181) is a promising blood biomarker however, it is unknown if levels increase in presymptomatic AD. Therefore,… read more here.
Keywords: plasma; tau181; alzheimer disease; non carriers ... See more keywords
Plasma P-tau181 in Alzheimer’s disease: relationship to other biomarkers, differential diagnosis, neuropathology and longitudinal progression to Alzheimer’s dementia
Sign Up to like & getrecommendations! Published in 2020 at "Nature Medicine"
DOI: 10.1038/s41591-020-0755-1
Abstract: Plasma phosphorylated tau181 (P-tau181) might be increased in Alzheimer’s disease (AD), but its usefulness for differential diagnosis and prognosis is unclear. We studied plasma P-tau181 in three cohorts, with a total of 589 individuals, including… read more here.
Keywords: dementia; alzheimer disease; tau181; plasma tau181 ... See more keywords
Diagnostic Performance and Clinical Applicability of Blood-Based Biomarkers in a Prospective Memory Clinic Cohort
Sign Up to like & getrecommendations! Published in 2022 at "Neurology"
DOI: 10.1212/wnl.0000000000201597
Abstract: Background and Objectives Blood-based biomarkers have emerged as minimally invasive options for evaluating cognitive impairment. Most studies to date have assessed them in research cohorts, limiting their generalization to everyday clinical practice. We evaluated their… read more here.
Keywords: tau181; non neurodegenerative; plasma; memory ... See more keywords
Correlation between cognitive impairment and serum phosphorylated tau181 protein in patients with preeclampsia
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Aging Neuroscience"
DOI: 10.3389/fnagi.2023.1148518
Abstract: Objective To study the cognitive function status, serum phosphorylated tau181 (P-tau181) protein level, and total tau (T-tau) protein level in patients with preeclampsia (PE), pregnant healthy controls (PHCs), and non-pregnant healthy controls (NPHCs), and to… read more here.
Keywords: tau181 protein; tau; serum; tau181 ... See more keywords