Tau Proteins and Tauopathies in Alzheimer’s Disease
Sign Up to like & getrecommendations! Published in 2017 at "Cellular and Molecular Neurobiology"
DOI: 10.1007/s10571-017-0574-1
Abstract: Alzheimer’s disease (AD) is characterized by progressive memory loss and cognitive function deficits. There are two major pathological hallmarks that contribute to the pathogenesis of AD which are the presence of extracellular amyloid plaques composed… read more here.
Keywords: proteins tauopathies; tau; tauopathies alzheimer; alzheimer disease ... See more keywords
An evaluation of Drosophila as a model system for studying tauopathies such as Alzheimer’s disease
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Neuroscience Methods"
DOI: 10.1016/j.jneumeth.2019.01.001
Abstract: Work spanning almost two decades using the fruit fly, Drosophila melanogaster, to study tau-mediated neurodegeneration has provided valuable and novel insights into the causes and mechanisms of tau-mediated toxicity and dysfunction in tauopathies such as… read more here.
Keywords: drosophila; tauopathies alzheimer; system; alzheimer disease ... See more keywords