Selective impairment of circuits between prefrontal cortex glutamatergic neurons and basal forebrain cholinergic neurons in a tauopathy mouse model.
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DOI: 10.1093/cercor/bhac036
Abstract: Alzheimer's disease (AD) is a prevalent neurodegenerative disorder linked to cognitive decline. To understand how specific neuronal circuits are impaired in AD, we have used optogenetic and electrophysiological approaches to reveal the functional changes between… read more here.
Keywords: cholinergic neurons; pfc; cortex; model ... See more keywords