Evaluation of acute and subacute toxicity of sodium taurodeoxycholate in rats
Sign Up to like & getrecommendations! Published in 2019 at "Drug and Chemical Toxicology"
DOI: 10.1080/01480545.2019.1609493
Abstract: Abstract Taurodeoxycholate (TDCA) inhibits various inflammatory responses suggesting potential clinical application. However, the toxicity of TDCA has not been evaluated in detail in vivo. We investigated the acute toxicity and 4-week repeated-dose toxicity of TDCA… read more here.
Keywords: acute subacute; tdca; toxicity; subacute toxicity ... See more keywords
Oral Administration of Taurodeoxycholate, A GPCR19 Agonist, Effectively Ameliorates Atopic Dermatitis in A Mouse Model
Sign Up to like & getrecommendations! Published in 2024 at "Experimental Dermatology"
DOI: 10.1111/exd.15193
Abstract: Atopic dermatitis (AD) is the most prevalent chronic inflammatory skin disorder, characterised by intense pruritus and recurrent eczematous lesions. Recently, the US FDA has approved Janus kinase (JAK) inhibitors for oral treatment in AD patients.… read more here.
Keywords: oral administration; taurodeoxycholate; gpcr19 agonist; atopic dermatitis ... See more keywords