Microtubule Engagement with Taxane Is Altered in Taxane-Resistant Gastric Cancer
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DOI: 10.1158/1078-0432.ccr-19-3018
Abstract: Purpose: Although taxane-based therapy is standard treatment for advanced gastric cancer, a majority of patients exhibit intrinsic resistance to taxanes. Here, we aim to identify the molecular basis of taxane resistance in gastric cancer. Experimental… read more here.
Keywords: taxane resistance; drug; taxane; cancer ... See more keywords
Abstract P6-03-21: Identification of mechanisms driving acquired chemoresistance in preclinical breast cancer models of taxane resistance
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DOI: 10.1158/1538-7445.sabcs19-p6-03-21
Abstract: Background: Taxanes are an established part of the treatment regime for early and metastatic breast cancer. However acquired chemoresistance remains a major factor in therapeutic failure in these patients. Treatment options thereafter are limited. It… read more here.
Keywords: cancer; acquired chemoresistance; taxane resistance; breast cancer ... See more keywords