Molybdenum sulfide-based electrochemical platform for high sensitive detection of taxifolin in Chinese medicine.
Sign Up to like & getrecommendations! Published in 2020 at "Analytica chimica acta"
DOI: 10.1016/j.aca.2019.11.057
Abstract: MoS2 and nitrogen doped active carbon composite (MoS2/ANC) is fabricated to detect taxifolin and exhibits superior redox current response and decreased redox potential difference. Further investigation reveals that the kinetic process of the redox reaction… read more here.
Keywords: medicine; sulfide based; detection; molybdenum sulfide ... See more keywords
Taxifolin enhances osteogenic differentiation of human bone marrow mesenchymal stem cells partially via NF-κB pathway.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.06.002
Abstract: Taxifolin, a flavonoid compound, has been reported to stimulate osteogenic differentiation in osteoblasts. The present study investigated whether taxifolin affects the osteogenic differentiation of human bone marrow mesenchymal stem cells (hBMSCs) and the molecular mechanisms… read more here.
Keywords: human bone; differentiation human; pathway; osteogenic differentiation ... See more keywords
Chitosan composite microparticles: A promising gastroadhesive system for taxifolin.
Sign Up to like & getrecommendations! Published in 2019 at "Carbohydrate polymers"
DOI: 10.1016/j.carbpol.2019.04.075
Abstract: Taxifolin possesses gastroprotective property but is characterized by low water solubility, is instabile in alkaline medium, and is degraded by the intestinal bacteria flora. The purpose of the work was therefore to produce a gastroadhesive… read more here.
Keywords: promising gastroadhesive; chitosan composite; taxifolin; microparticles promising ... See more keywords
A new electrochemical sensor for Taxifolin based on RGO-Co3S4@MoS2 modified electrode
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Electroanalytical Chemistry"
DOI: 10.1016/j.jelechem.2019.113473
Abstract: Abstract A novel electrochemical sensor was designed and constructed for high-sensitive detection of Taxifolin based on Co3S4@MoS2 loaded on reduced graphene oxide (RGO-Co3S4@MoS2) as modified materials. It’s the first time for Co3S4@MoS2 was exploited to… read more here.
Keywords: mos2; co3s4 mos2; electrochemical sensor; taxifolin ... See more keywords
Taxifolin stability: In silico prediction and in vitro degradation with HPLC-UV/UPLC–ESI-MS monitoring
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Pharmaceutical Analysis"
DOI: 10.1016/j.jpha.2020.06.008
Abstract: Taxifolin has a plethora of therapeutic activities and is currently isolated from the stem bark of the tree Larix gmelinni (Dahurian larch). It is a flavonoid of high commercial interest for its use in supplements… read more here.
Keywords: degradation; taxifolin; uplc esi; stability ... See more keywords
Ameliorative effect of taxifolin on gentamicin-induced ototoxicity via down-regulation of apoptotic pathways in mouse cochlear UB/OC-2 cells
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the Chinese Medical Association"
DOI: 10.1097/jcma.0000000000000708
Abstract: Background: Taxifolin is a flavanonol with efficacious cytoprotective properties, such as anti-inflammatory, antioxidant, anticancer, hepatoprotective, and nephroprotective effects. However, the potential protective effects of taxifolin against gentamicin-induced ototoxicity have not been confirmed. In this study,… read more here.
Keywords: gentamicin induced; taxifolin gentamicin; taxifolin; cochlear cells ... See more keywords
Taxifolin Inhibits Receptor Activator of NF-κB Ligand-Induced Osteoclastogenesis of Human Bone Marrow-Derived Macrophages in vitro and Prevents Lipopolysaccharide-Induced Bone Loss in vivo
Sign Up to like & getrecommendations! Published in 2018 at "Pharmacology"
DOI: 10.1159/000495254
Abstract: It has been reported that taxifolin inhibit osteoclastogenesis in RAW264.7 cells. In our research, the inhibition effects of taxifolin on the osteoclastogenesis of human bone marrow-derived macrophages (BMMs) induced by receptor activator of NF-κB ligand… read more here.
Keywords: marrow derived; osteoclastogenesis human; human bone; taxifolin ... See more keywords
Taxifolin inhibits amyloid-β oligomer formation and fully restores vascular integrity and memory in cerebral amyloid angiopathy
Sign Up to like & getrecommendations! Published in 2017 at "Acta Neuropathologica Communications"
DOI: 10.1186/s40478-017-0429-5
Abstract: Cerebral amyloid angiopathy (CAA) induces various forms of cerebral infarcts and hemorrhages from vascular amyloid-β accumulation, resulting in acceleration of cognitive impairment, which is currently untreatable. Soluble amyloid-β protein likely impairs cerebrovascular integrity as well… read more here.
Keywords: memory; amyloid; caa; taxifolin ... See more keywords
Fertility protective effect of taxifolin in cisplatin-induced ovarian damage.
Sign Up to like & getrecommendations! Published in 2022 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_202210_29909
Abstract: OBJECTIVE The aim of our study was to investigate the protective effect of taxifolin on ovarian damage and reproductive dysfunction created by cisplatin administration. MATERIALS AND METHODS A total of 36 albino Wistar female adult… read more here.
Keywords: damage; group; cisplatin; taxifolin ... See more keywords
Statement on the safety of taxifolin‐rich extract from Dahurian Larch (Larix gmelinii)
Sign Up to like & getrecommendations! Published in 2017 at "EFSA Journal"
DOI: 10.2903/j.efsa.2017.5059
Abstract: Abstract Following a request from the European Commission, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to carry out a supplementary safety assessment for taxifolin by considering also those population groups… read more here.
Keywords: dahurian larch; rich extract; extract dahurian; taxifolin rich ... See more keywords
Taxifolin for prevention of COGnitive impairment (T-COG trial): a study protocol for a randomized, double-blind, placebo-controlled trial
Sign Up to like & getrecommendations! Published in 2025 at "Frontiers in Nutrition"
DOI: 10.3389/fnut.2025.1686381
Abstract: Background In 2023 and 2024, the novel anti-β-amyloid antibodies lecanemab and donanemab have been approved for treatment of mild cognitive impairment and mild dementia in several countries, including Japan and the United States. Although they… read more here.
Keywords: cognitive impairment; trial; randomized double; placebo ... See more keywords