Combined treatment of Ketogenic diet and propagermanium reduces neuroinflammation in Tay-Sachs disease mouse model
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DOI: 10.1007/s11011-025-01553-6
Abstract: Tay-Sachs disease is a rare lysosomal storage disorder caused by β-Hexosaminidase A enzyme deficiency causing abnormal GM2 ganglioside accumulation in the central nervous system. GM2 accumulation triggers chronic neuroinflammation due to neurodegeneration-based astrogliosis and macrophage… read more here.
Keywords: disease; ketogenic diet; neuroinflammation; propagermanium ... See more keywords