The role of Hippo‐YAP/TAZ signaling in brain development
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DOI: 10.1002/dvdy.504
Abstract: In order for our complex nervous system to develop normally, both precise spatial and temporal regulation of a number of different signaling pathways is critical. During both early embryogenesis and in organ development, one pathway… read more here.
Keywords: taz signaling; role; brain development; development ... See more keywords
Hippo-TAZ signaling is the master regulator of the onset of triple-negative basal-like breast cancers
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2123134119
Abstract: Significance A universal oncogenic driver of basal-like breast cancer (BLBC) has resisted identification. We show that continuous transcriptional coactivator with PDZ-binding motif (TAZ) activation in precancerous murine luminal cells generates luminal cancers that later become… read more here.
Keywords: like breast; basal like; taz signaling; hippo taz ... See more keywords