WNK1 phosphorylation sites in TBC1D1 and TBC1D4 modulate cell surface expression of GLUT1.
Sign Up to like & getrecommendations! Published in 2019 at "Archives of biochemistry and biophysics"
DOI: 10.1016/j.abb.2019.108223
Abstract: Glucose uptake by mammalian cells is a key mechanism to maintain cell and tissue homeostasis and relies mostly on plasma membrane-localized glucose transporter proteins (GLUTs). Two main cellular mechanisms regulate GLUT proteins in the cell:… read more here.
Keywords: surface; tbc1d4; expression; glut1 ... See more keywords
The effect of diabetes and the diabetogenic TBC1D4 p.Arg684ter variant on kidney function in Inuit in Greenland
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Circumpolar Health"
DOI: 10.1080/22423982.2023.2191406
Abstract: ABSTRACT The aim of this study was to examine the effect of diabetes and the diabetogenic TBC1D4 variant on kidney function in Greenland in a population-based setting. Health survey data and TBC1D4 genotypes from 5,336… read more here.
Keywords: kidney; effect diabetes; tbc1d4 variant; diabetes diabetogenic ... See more keywords