A multi pathway coupled domino strategy: I2/TBHP-promoted synthesis of imidazopyridines and thiazoles via sp3, sp2 and sp C–H functionalization
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DOI: 10.1039/d1ra07438e
Abstract: I2/TBHP-promoted, one-pot, multi pathway synthesis of imidazopyridines and thiazoles has been achieved through readily available ethylarenes, ethylenearenes and ethynearenes. I2/TBHP as an initiator and oxidant is used to realize the C–H functionalization of this domino… read more here.
Keywords: tbhp promoted; imidazopyridines thiazoles; functionalization; synthesis imidazopyridines ... See more keywords
I2/TBHP-Promoted Approach to α-Keto Esters from Trifluoromethyl β-Diketones and Alcohols via C–C Bond Cleavage
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DOI: 10.1055/s-0036-1588833
Abstract: A metal-free oxidative coupling reaction of trifluoromethyl β-diketones with alcohols for the synthesis of α-keto esters in good to excellent yields has been developed. Preliminary mechanistic studies suggest that an I2/TBHP promoted sequential iodination, C–C… read more here.
Keywords: diketones alcohols; bond; tbhp promoted; keto esters ... See more keywords