TBL1 Inhibition Eradicates Drug Resistant Leukemia Initiating Cells in T-ALL
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DOI: 10.1182/blood-2024-208681
Abstract: BACKGROUND: Relapse in T-cell acute lymphoblastic leukemia (T-ALL) following chemotherapy remains a therapeutic challenge, necessitating novel treatment approaches. Aberrant activation of the Wnt pathway, particularly through β-catenin, is commonly observed in T-ALL, and plays a… read more here.
Keywords: relapse; tegavivint; tbl1; mice ... See more keywords