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   Articles with "tbl1xr1" as a keyword



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A case of West syndrome and global developmental delay in a child with a heterozygous mutation in the TBL1XR1 gene: A case report

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recommendations! Published in 2023 at "Medicine"

DOI: 10.1097/md.0000000000033744

Abstract: Background: TBL1XR1, also known as IRA1 or TBLR1, encodes a protein that is localized in the nucleus and is expressed in most tissues. TBL1XR1 binds to histones H2B and H4 in vitro and functions in… read more here.

Keywords: tbl1xr1 gene; tbl1xr1; child; case ... See more keywords
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Deficiency of TBL1XR1 causes asthenozoospermia

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recommendations! Published in 2021 at "Andrologia"

DOI: 10.1111/and.13980

Abstract: Transducin (β)‐like 1 X‐linked receptor 1 (TBL1XR1) is an evolutionarily conserved protein related to spermatozoa. To clarify its role and mechanism of action in spermatozoa, qRT‐PCR was used to analyse the expression of TBL1XR1 in… read more here.

Keywords: tbl1xr1; spermatozoa; deficiency tbl1xr1; causes asthenozoospermia ... See more keywords
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MicroRNA-34c-5p Reduces Malignant Properties of Lung Cancer Cells through Regulation of TBL1XR1/Wnt/β-catenin Signaling.

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recommendations! Published in 2023 at "Current molecular medicine"

DOI: 10.2174/1566524023666230330083819

Abstract: INTRODUCTION Lung cancer is common cancer with high mortality. A growing number of studies have focused on investigating the regulatory effects of microRNAs (miRs/miRNAs) during cancer progression. Nevertheless, the biological function of miR34c-5p in lung… read more here.

Keywords: lung cancer; cancer cells; mir 34c; wnt catenin ... See more keywords
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TBL1XR1 Ensures Balanced Neural Development Through NCOR Complex-Mediated Regulation of the MAPK Pathway

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recommendations! Published in 2021 at "Frontiers in Cell and Developmental Biology"

DOI: 10.3389/fcell.2021.641410

Abstract: TBL1XR1 gene is associated with multiple developmental disorders presenting several neurological aspects. The relative protein is involved in the modulation of important cellular pathways and master regulators of transcriptional output, including nuclear receptor repressors, Wnt… read more here.

Keywords: tbl1xr1; regulation mapk; ncor complex; regulation ... See more keywords