Innovative pulmonary targeting of terbutaline sulfate-laded novasomes for non-invasive tackling of asthma: statistical optimization and comparative in vitro/in vivo evaluation
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DOI: 10.1080/10717544.2022.2092236
Abstract: Abstract Asthma represents a globally serious non-communicable ailment with significant public health outcomes for both pediatrics and adults triggering vast morbidity and fatality in critical cases. The β2-adrenoceptor agonist, terbutaline sulfate (TBN), is harnessed as… read more here.
Keywords: vitro; tbn; terbutaline sulfate; pulmonary targeting ... See more keywords
Nephroprotective Effects of Tetramethylpyrazine Nitrone TBN in Diabetic Kidney Disease
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DOI: 10.3389/fphar.2021.680336
Abstract: Diabetic kidney disease (DKD) is the leading cause of end-stage renal failure, but therapeutic options for nephroprotection are limited. Oxidative stress plays a key role in the pathogenesis of DKD. Our previous studies demonstrated that… read more here.
Keywords: nitrone tbn; tbn; diabetic kidney; tetramethylpyrazine nitrone ... See more keywords
Tetramethylpyrazine nitrone activates hypoxia-inducible factor and regulates iron homeostasis to improve renal anemia
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DOI: 10.3389/fphar.2022.964234
Abstract: Renal anemia is one of the most common complications of chronic kidney disease and diabetic kidney disease. Despite the progress made in recent years, there is still an urgent unmet clinical need for renal anemia… read more here.
Keywords: inducible factor; tbn; hypoxia inducible; renal anemia ... See more keywords