The kinetoplastid-specific phosphatase KPP1 attenuates PLK activity to facilitate flagellum inheritance in Trypanosoma brucei
Sign Up to like & getrecommendations! Published in 2021 at "Science Signaling"
DOI: 10.1126/scisignal.abc6435
Abstract: Flagellum inheritance in trypanosomes requires strategically timed suppression of Polo-like kinase activity. Passing the flagellum in trypanosomes The single flagellum of the unicellular parasite Trypanosoma brucei is critical for virulence, and Polo-like kinase (TbPLK) is… read more here.
Keywords: flagellum inheritance; inheritance; activity; flagellum ... See more keywords
CRL4WDR1 Controls Polo-like Kinase Protein Abundance to Promote Bilobe Duplication, Basal Body Segregation and Flagellum Attachment in Trypanosoma brucei
Sign Up to like & getrecommendations! Published in 2017 at "PLoS Pathogens"
DOI: 10.1371/journal.ppat.1006146
Abstract: The Polo-like kinase homolog in Trypanosoma brucei, TbPLK, plays essential roles in basal body segregation, flagellum attachment and cytokinesis. The level of TbPLK protein is tightly controlled, but the underlying mechanism remains elusive. Here, we… read more here.
Keywords: protein; basal body; bilobe; tbplk ... See more keywords