Structural Basis of Protein Arginine Methyltransferase Activation by a Catalytically Dead Homolog (Prozyme).
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DOI: 10.1016/j.jmb.2019.11.002
Abstract: Prozymes are pseudoenzymes that stimulate the function of weakly active enzymes through complex formation. The major Trypanosoma brucei protein arginine methyltransferase, TbPRMT1 enzyme (ENZ), requires TbPRMT1 prozyme (PRO) to form an active heterotetrameric complex. Here… read more here.
Keywords: structural basis; arginine methyltransferase; methyltransferase; protein arginine ... See more keywords