tBuOK/DMSO/O2 Catalyzed direct α-C(sp3)-H Alkylation with Styrenes: productive α-amino radical for hydroaminoalkylation
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DOI: 10.1039/d2qo01911f
Abstract: Direct α-C(sp3)-H alkylation of hydroaminoalkylation (HAA) catalyzed by tBuOK/DMSO/O2 from α-aryl benzylamines with styrenes is reported. The reaction has delivered diverse selectively substituted amines and N-heterocycles under mild conditions, showing... read more here.
Keywords: sp3 alkylation; direct sp3; hydroaminoalkylation; tbuok dmso ... See more keywords