Characterization and function of the T-box 1 gene in Chinese giant salamander Andrias davidianus.
Sign Up to like & getrecommendations! Published in 2018 at "Genomics"
DOI: 10.1016/j.ygeno.2018.09.007
Abstract: We characterized the Andrias davidianus T-box 1 (Tbx1) gene. Tbx1 expression was high in testis and low in other examined tissues. Immunohistochemistry detected tbx1 expression in somatic and germ cells 62 days post-hatching (dph), prior to… read more here.
Keywords: tbx1; tbx1 expression; andrias davidianus; expression ... See more keywords
Tbx1 regulates extracellular matrix-cell interactions in the second heart field.
Sign Up to like & getrecommendations! Published in 2019 at "Human molecular genetics"
DOI: 10.1093/hmg/ddz058
Abstract: Tbx1, the major candidate gene for DiGeorge or 22q11.2 deletion syndrome, is required for efficient incorporation of cardiac progenitors of the second heart field (SHF) into the heart. However, the mechanisms by which TBX1 regulates… read more here.
Keywords: tbx1; heart; tbx1 regulates; extracellular matrix ... See more keywords
Loss of CXCL12/CXCR4 signalling impacts several aspects of cardiovascular development but does not exacerbate Tbx1 haploinsufficiency
Sign Up to like & getrecommendations! Published in 2018 at "PLoS ONE"
DOI: 10.1371/journal.pone.0207251
Abstract: The CXCL12-CXCR4 pathway has crucial roles in stem cell homing and maintenance, neuronal guidance, cancer progression, inflammation, remote-conditioning, cell migration and development. Recently, work in chick suggested that signalling via CXCR4 in neural crest cells… read more here.
Keywords: cxcl12 cxcr4; tbx1; cxcl12; tbx1 haploinsufficiency ... See more keywords