Impact of cardiac resynchronization therapy on circulating IL-17 producing cells in patients with advanced heart failure
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Interventional Cardiac Electrophysiology"
DOI: 10.1007/s10840-018-0491-3
Abstract: PurposeIL-17-producing T cells have been implicated in the inflammatory milieu of chronic heart failure (CHF), which implies a dismal prognosis in affected patients. The aim of this study was to evaluate the impact of cardiac… read more here.
Keywords: impact cardiac; tc17 cells; producing cells; heart failure ... See more keywords
Tissue adaptation
Sign Up to like & getrecommendations! Published in 2019 at "Nature Immunology"
DOI: 10.1038/s41590-018-0306-9
Abstract: Commensals and commensal-reactive lymphocytes coexist at barrier tissues. In Science, Belkaid and colleagues show that skin-resident commensal-specific T cells express a type 17 program associated with a poised type 2 program. Staphylococcus epidermis–colonized mice develop… read more here.
Keywords: tc17 cells; tissue adaptation; tissue; epidermis specific ... See more keywords
The Age-Dependent Role of Th22, Tc22, and Tc17 Cells in the Severity of Pneumonia in COVID-19 Immunopathogenesis.
Sign Up to like & getrecommendations! Published in 2022 at "Viral immunology"
DOI: 10.1089/vim.2021.0132
Abstract: Coronavirus disease 2019 (COVID-19) has clinical manifestations ranging from mild symptoms to respiratory failure, septic shock, and multi-organ failure. Lymphocytes are divided into different subtypes based on their cytokine production pattern. In this study, we… read more here.
Keywords: severity pneumonia; tc17; role; th22 tc22 ... See more keywords
Lesional activation of Tc17 cells in Behçet disease and psoriasis supports HLA class I‐mediated autoimmune responses *
Sign Up to like & getrecommendations! Published in 2021 at "British Journal of Dermatology"
DOI: 10.1111/bjd.20643
Abstract: Behçet disease (BD) presents with lymphocytic and neutrophilic vasculitis of unknown aetiology. HLA‐B*51, the endoplasmic reticulum aminopeptidase 1 (ERAP1), and interleukin 23 receptor (IL23R)/IL12R are genetic risk factors. IL‐23 regulates IL‐17A, which controls the recruitment… read more here.
Keywords: beh disease; tc17 cells; disease; lesional activation ... See more keywords
Expansion of Th/Tc17 T Cells and Loss of CX3CR1+ Macrophages Play a Critical Role in the Pathogenesis of Steroid-Refractory Acute Intestinal Gvhd
Sign Up to like & getrecommendations! Published in 2019 at "Blood"
DOI: 10.1182/blood-2019-126261
Abstract: Acute gut graft-versus-host disease (GVHD) is the major contributor to mortality and morbidity of allogeneic hematopoietic stem cell transplantation recipients. Steroids are the first-line therapy for acute GVHD, but approximately 30% of patients develop steroid… read more here.
Keywords: tc17 cells; acute gvhd; dex; recipients grafted ... See more keywords
PD-1 limits differentiation and plasticity of Tc17 cells
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1104730
Abstract: Blockade of surface co-inhibitory receptor programmed cell death-1 (PD-1; CD279) has been established as an important immunotherapeutic approach to treat malignancies. On a cellular level, PD-1 is demonstrated to be of particular importance in inhibiting… read more here.
Keywords: tc17; differentiation plasticity; expression; tc17 cells ... See more keywords