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Published in 2018 at "Toxicological Sciences"
DOI: 10.1093/toxsci/kfx199
Abstract: A dynamic model based on ordinary differential equations that describes uptake, basolateral and canalicular export of taurocholic acid (TCA) in human HepaRG cells is presented. The highly reproducible inter-assay experimental data were used to reliably…
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Keywords:
heparg cells;
tca clearance;
model;
clearance ... See more keywords