HuR stabilizes lnc-Sox5 mRNA to promote tongue carcinogenesis
Sign Up to like & getrecommendations! Published in 2017 at "Biochemistry (Moscow)"
DOI: 10.1134/s0006297917040046
Abstract: Long noncoding RNAs (lncRNAs) have been recently regarded as systemic regulators in multiple biological processes including tumorigenesis. In this study, we report an ultra-highly expressed lncRNA, lnc-Sox5, in tongue tumor tissues. The results imply that… read more here.
Keywords: lnc sox5; tca8113; sox5; hur ... See more keywords
HIF-1α restricts proliferation and apoptosis of Tca8113 cells through up regulation of Hippo signaling pathway under hypoxic conditions.
Sign Up to like & getrecommendations! Published in 2018 at "European Review for Medical and Pharmacological Sciences"
DOI: 10.26355/eurrev_201810_16151
Abstract: OBJECTIVE: The hypoxia-inducible factor-1α (HIF-1α) is a key factor for tumor cells adaptation to hypoxia. Studies have shown that under hypoxic conditions, HIF-1α expression was significantly increased in human tongue squamous cell carcinoma cells (Tca8113).… read more here.
Keywords: tca8113 cells; tca8113; hypoxic conditions; proliferation ... See more keywords