Transcutaneous bilirubin measurements: useful, but also reproducible?
Sign Up to like & getrecommendations! Published in 2020 at "Pediatric Research"
DOI: 10.1038/s41390-020-01242-3
Abstract: Jaundice is the most frequent clinical problem in both preterm and term infants, and it has been reported that ~80% develop unconjugated hyperbilirubinemia. Fortunately, only a small but non-negligible proportion of these infants progresses to… read more here.
Keywords: tcb; tcb devices; mol; transcutaneous bilirubin ... See more keywords
Transcutaneous Bilirubin Monitoring in Preterm Infants of 23 to 34 Weeks' Gestation.
Sign Up to like & getrecommendations! Published in 2021 at "American journal of perinatology"
DOI: 10.1055/s-0041-1731277
Abstract: OBJECTIVE The study aimed to evaluate the validity of transcutaneous bilirubin (TcB) measurements at three sites in premature infants born at 230/7 to 346/7 weeks' gestational age (GA) compared with total serum bilirubin (TSB) measurements.… read more here.
Keywords: tcb measurements; tcb; cohort; preterm infants ... See more keywords
Potent nonopioid antinociceptive activity of telocinobufagin in models of acute pain in mice
Sign Up to like & getrecommendations! Published in 2019 at "Pain Reports"
DOI: 10.1097/pr9.0000000000000791
Abstract: Abstract Introduction: In recent decades, several researches have been conducted in search of new analgesics that do not present the side effects of opioids. In this context, animal venoms contain natural painkillers that have been… read more here.
Keywords: mice; pain; tcb; antinociceptive activity ... See more keywords
Transcutaneous bilirubinometry during and after phototherapy in preterm infants: a prospective observational study
Sign Up to like & getrecommendations! Published in 2020 at "BMJ Paediatrics Open"
DOI: 10.1136/bmjpo-2020-000681
Abstract: Objective To examine the accuracy of transcutaneous bilirubinometry (TCB) measurements during and after phototherapy (PT) in preterm infants. Design Prospective observational cohort study. Setting Level III neonatal centre. Patients Preterm infants (from 23+0 to 36+6… read more here.
Keywords: agreement; phototherapy preterm; transcutaneous bilirubinometry; tsb ... See more keywords
JAK and mTOR inhibitors prevent cytokine release while retaining T cell bispecific antibody in vivo efficacy
Sign Up to like & getrecommendations! Published in 2022 at "Journal for Immunotherapy of Cancer"
DOI: 10.1136/jitc-2021-003766
Abstract: Background T cell engaging therapies, like chimeric antigen receptor T cells and T cell bispecific antibodies (TCBs), efficiently redirect T cells towards tumor cells, facilitating the formation of a cytotoxic synapse and resulting in subsequent… read more here.
Keywords: cell; tcb; jak; release ... See more keywords
Abstract 4117: Molecular insights into resistance mechanisms to therapy with T cell bispecific antibodies
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-4117
Abstract: T Cell Bispecific Antibodies (TCBs) are potent molecules that induce durable complete remissions with a favorable safety profile in Relapsed Refractory Non Hodgkin Lymphoma patients. Despite the promising clinical efficacy, a proportion of patients escape… read more here.
Keywords: cell; cancer; tcb; resistance ... See more keywords
Use of Transcutaneous Bilirubin to Determine the Need for Phototherapy in Resource-Limited Settings
Sign Up to like & getrecommendations! Published in 2017 at "Neonatology"
DOI: 10.1159/000452788
Abstract: Background: Routine and timely determination of total serum bilirubin (TSB) remains a challenge in many resource-limited countries with substantial burden of severe neonatal hyperbilirubinemia. Limited evidence exists on the potential usefulness of transcutaneous bilirubin (TcB)… read more here.
Keywords: resource limited; tsb; bilirubin; tcb ... See more keywords
A Prospective Comparison of Transcutaneous and Serum Bilirubin Within Brief Time Intervals
Sign Up to like & getrecommendations! Published in 2017 at "Clinical Pediatrics"
DOI: 10.1177/0009922817701170
Abstract: The American Academy of Pediatrics recommends screening newborns ≥35 weeks’ gestation with total serum bilirubin (TSB) or transcutaneous bilirubin (TcB) to detect hyperbilirubinemia. Retrospective studies show TcB measurements strongly correlate with TSB; however, few prospective… read more here.
Keywords: tsb; bilirubin; tcb; serum bilirubin ... See more keywords
CD20-TCB, a Novel T-Cell-Engaging Bispecific Antibody, Can be Safely Combined with the Anti-PD-L1 Antibody Atezolizumab in Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma
Sign Up to like & getrecommendations! Published in 2019 at "Blood"
DOI: 10.1182/blood-2019-123978
Abstract: CD20-TCB (RG6026) is a novel T-cell-engaging bispecific (TCB) antibody with a '2:1' molecular format that comprises two fragment antigen binding regions that bind CD20 (on the surface of B cells) and one that binds CD3… read more here.
Keywords: research; cd20 tcb; tcb; cell ... See more keywords
Development of a mobile phone camera-based transcutaneous bilirubinometer for low-resource settings
Sign Up to like & getrecommendations! Published in 2022 at "Biomedical Optics Express"
DOI: 10.1364/boe.449625
Abstract: Newborns in high-income countries are routinely screened for neonatal jaundice using transcutaneous bilirubinometery (TcB). In low-and middle-income countries, TcB is not widely used due to a lack of availability; however, mobile-phone approaches for TcB could… read more here.
Keywords: phone camera; mobile phone; low resource; tcb ... See more keywords
Sixth-Hour Trancutaneous Bilirubin and Need for Phototherapy in DAT Positive Newborns.
Sign Up to like & getrecommendations! Published in 2022 at "Pediatrics"
DOI: 10.1542/peds.2021-054071
Abstract: OBJECTIVES To characterize the outcomes of ABO incompatible direct antiglobulin test (DAT) positive newborns and determine the predictive ability of a sixth-hour transcutaneous bilirubin (TcB for needing phototherapy ≤24 hours of age. METHODS Retrospective, cross-sectional… read more here.
Keywords: positive newborns; tcb; sixth hour; dat positive ... See more keywords