Discordant rearrangement of primary and anamnestic CD8+ T cell responses to influenza A viral epitopes upon exposure to bacterial superantigens: Implications for prophylactic vaccination, heterosubtypic immunity and superinfections
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DOI: 10.1371/journal.ppat.1008393
Abstract: Infection with (SAg)-producing bacteria may precede or follow infection with or vaccination against influenza A viruses (IAVs). However, how SAgs alter the breadth of IAV-specific CD8+ T cell (TCD8) responses is unknown. Moreover, whether recall… read more here.
Keywords: cd8 cell; heterosubtypic immunity; prophylactic vaccination; tcd8 ... See more keywords
Rickettsia Vaccine Candidate pVAX1-OmpB24 Stimulates TCD4+INF-γ+ and TCD8+INF-γ+ Lymphocytes in Autologous Co-Culture of Human Cells
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DOI: 10.3390/vaccines11010173
Abstract: Background: In recent years, promising vaccination strategies against rickettsiosis have been described in experimental animal models and human cells. OmpB is considered an immunodominant antigen that is recognized by T and B cells. The aim… read more here.
Keywords: pvax1 ompb24; inf; tcd4 inf; tcd8 ... See more keywords