CD44 is a macrophage receptor for TcdB from Clostridioides difficile that via its lysine-158 succinylation contributes to inflammation
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DOI: 10.1080/19490976.2025.2506192
Abstract: ABSTRACT Toxin B (TcdB) is a critical virulence factor in Clostridioides difficile-associated disease (CDAD), which activates macrophages to promote inflammation and epithelial damage. However, the mechanism by which TcdB targets inflammation-related receptors on the macrophage… read more here.
Keywords: succinylation; macrophage; tcdb fbd; tcdb ... See more keywords