LAUSR

About LAUSR
Donate
Contact Us

Follow us:

You are not signed in:

Sign Up!


   Articles with "tcf1" as a keyword



Photo from wikipedia

Differential expression of LEF1/TCFs family members in colonic carcinogenesis

Sign Up to like & get
recommendations! Published in 2017 at "Molecular Carcinogenesis"

DOI: 10.1002/mc.22530

Abstract: Lef1/Tcfs family, which includes Lef1, Tcf1, Tcf3, and Tcf4, is required for the transcriptional activation induced by β‐catenin. However, whether all the members play the same role in colon carcinogenesis is not clear. We found… read more here.

Keywords: tcfs family; lef1 tcf1; tcf1; lef1 tcfs ... See more keywords
Photo by markusspiske from unsplash

β-catenin coordinates with Jup and the TCF1/GATA6 axis to regulate human embryonic stem cell fate.

Sign Up to like & get
recommendations! Published in 2017 at "Developmental biology"

DOI: 10.1016/j.ydbio.2017.09.004

Abstract: β-catenin-mediated signaling has been extensively studied in regard to its role in the regulation of human embryonic stem cells (hESCs). However, the results are controversial and the mechanism by which β-catenin regulates the hESC fate… read more here.

Keywords: hesc differentiation; catenin; tcf1; gata6 ... See more keywords
Photo by kirrender from unsplash

Tcf1 is essential for initiation of oncogenic Notch1-driven chromatin topology in T-ALL

Sign Up to like & get
recommendations! Published in 2022 at "Blood"

DOI: 10.1182/blood.2021012077

Abstract: Abstract NOTCH1 is a well-established lineage specifier for T cells and among the most frequently mutated genes throughout all subclasses of T cell acute lymphoblastic leukemia (T-ALL). How oncogenic NOTCH1 signaling launches a leukemia-prone chromatin… read more here.

Keywords: topology; oncogenic notch1; tcf1; tcf1 essential ... See more keywords
Photo from wikipedia

Decreased TCF1 and BCL11B expression predicts poor prognosis for patients with chronic lymphocytic leukemia

Sign Up to like & get
recommendations! Published in 2022 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2022.985280

Abstract: T cell immune dysfunction is a prominent characteristic of chronic lymphocytic leukemia (CLL) and the main cause of failure for immunotherapy and multi-drug resistance. There remains a lack of specific biomarkers for evaluating T cell… read more here.

Keywords: prognosis; tcf1; expression; tcf1 bcl11b ... See more keywords
Photo from wikipedia

Downregulation of TCF1 in HIV Infection Impairs T-cell Proliferative Capacity by Disrupting Mitochondrial Function

Sign Up to like & get
recommendations! Published in 2022 at "Frontiers in Microbiology"

DOI: 10.3389/fmicb.2022.880873

Abstract: Background Despite the benefits of antiretroviral therapy (ART) for people with HIV, T-cell dysfunction cannot be fully restored. Metabolic dysregulation is associated with dysfunction of HIV-1-specific T-cells. Exploration of the factors regulating metabolic fitness can… read more here.

Keywords: cell; function; hiv; tcf1 ... See more keywords