Disruption of MeCP2–TCF20 complex underlies distinct neurodevelopmental disorders
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2119078119
Abstract: Significance Loss-of-function mutations in MECP2 cause the neurological disorder Rett syndrome (RTT), but the precise molecular mechanism driving pathogenesis remains unclear. Using an unbiased approach to identify proteins that interact with MeCP2, we identified the… read more here.
Keywords: rtt; function; mecp2 tcf20; tcf20 complex ... See more keywords