LAUSR

About LAUSR
Donate
Contact Us

Follow us:

You are not signed in:

Sign Up!


   Articles with "tcf3" as a keyword



Rare TCF3 variants associated with pediatric B cell acute lymphoblastic leukemia.

Sign Up to like & get
recommendations! Published in 2023 at "Pediatric hematology and oncology"

DOI: 10.1080/08880018.2023.2201302

Abstract: Germline genetic variants influence development of pediatric B cell acute lymphoblastic leukemia (B-ALL). Genome-wide association studies (GWAS) have identified several pediatric B-ALL susceptibility loci. IKZF1 and PAX5, transcription factors involved in B cell development, have… read more here.

Keywords: cell; pediatric cell; development; tcf3 ... See more keywords
Photo from wikipedia

Transcription factor 3 (TCF3) combined with histone deacetylase 3 (HDAC3) down-regulates microRNA-101 to promote Burkitt lymphoma cell proliferation and inhibit apoptosis.

Sign Up to like & get
recommendations! Published in 2021 at "Bioengineered"

DOI: 10.1080/21655979.2021.1977557

Abstract: To explore the function of transcription factor 3 (TCF3) on the proliferation and apoptosis of Burkitt lymphoma cells and its mechanism. qRT-PCR was performed to determine the expression of TCF3, histone deacetylase 3 (HDAC3), and… read more here.

Keywords: mir 101; apoptosis; proliferation; tcf3 ... See more keywords

TCF3 gene rearrangements in pediatric B-cell acute lymphoblastic leukemia-A single center experience.

Sign Up to like & get
recommendations! Published in 2023 at "International journal of laboratory hematology"

DOI: 10.1111/ijlh.14072

Abstract: INTRODUCTION B-cell precursor acute lymphoblastic leukemia (BCP-ALL) is the most common neoplasm in children. One of the long known recurrent rearrangements in BCP-ALL is t(1;19)(q23;p13.3)/TCF3::PBX1. However, other TCF3 gene rearrangements were also described that are… read more here.

Keywords: tcf3; gene rearrangements; lymphoblastic leukemia; acute lymphoblastic ... See more keywords

TCF3 and ID3 Regulate TSPAN32 Expression in Burkitt Lymphoma

Sign Up to like & get
recommendations! Published in 2025 at "Scandinavian Journal of Immunology"

DOI: 10.1111/sji.70040

Abstract: Burkitt lymphoma (BL) is an aggressive non‐Hodgkin B‐cell lymphoma characterised by chromosomal translocations involving the MYC gene, leading to its overexpression and driving uncontrolled proliferation. BL is categorised into endemic, sporadic, and immunodeficiency‐associated subtypes, each… read more here.

Keywords: tspan32; tcf3; tspan32 expression; burkitt lymphoma ... See more keywords

TCF3 downregulation alleviates renal fibrosis via PI3K/Akt/mTOR pathway inhibition and autophagy restoration in diabetic nephropathy

Sign Up to like & get
recommendations! Published in 2025 at "Frontiers in Medicine"

DOI: 10.3389/fmed.2025.1547410

Abstract: Background Diabetic nephropathy (DN) is characterized by tubular injury and tubulointerstitial fibrosis, leading to progressive renal dysfunction. While dysregulation of autophagy has been linked to DN pathogenesis, the underlying regulatory mechanisms remain incompletely understood. This… read more here.

Keywords: fibrosis; akt mtor; tcf3; expression ... See more keywords