Rare TCF3 variants associated with pediatric B cell acute lymphoblastic leukemia.
Sign Up to like & getrecommendations! Published in 2023 at "Pediatric hematology and oncology"
DOI: 10.1080/08880018.2023.2201302
Abstract: Germline genetic variants influence development of pediatric B cell acute lymphoblastic leukemia (B-ALL). Genome-wide association studies (GWAS) have identified several pediatric B-ALL susceptibility loci. IKZF1 and PAX5, transcription factors involved in B cell development, have… read more here.
Keywords: cell; pediatric cell; development; tcf3 ... See more keywords
Transcription factor 3 (TCF3) combined with histone deacetylase 3 (HDAC3) down-regulates microRNA-101 to promote Burkitt lymphoma cell proliferation and inhibit apoptosis.
Sign Up to like & getrecommendations! Published in 2021 at "Bioengineered"
DOI: 10.1080/21655979.2021.1977557
Abstract: To explore the function of transcription factor 3 (TCF3) on the proliferation and apoptosis of Burkitt lymphoma cells and its mechanism. qRT-PCR was performed to determine the expression of TCF3, histone deacetylase 3 (HDAC3), and… read more here.
Keywords: mir 101; apoptosis; proliferation; tcf3 ... See more keywords
TCF3 gene rearrangements in pediatric B-cell acute lymphoblastic leukemia-A single center experience.
Sign Up to like & getrecommendations! Published in 2023 at "International journal of laboratory hematology"
DOI: 10.1111/ijlh.14072
Abstract: INTRODUCTION B-cell precursor acute lymphoblastic leukemia (BCP-ALL) is the most common neoplasm in children. One of the long known recurrent rearrangements in BCP-ALL is t(1;19)(q23;p13.3)/TCF3::PBX1. However, other TCF3 gene rearrangements were also described that are… read more here.
Keywords: tcf3; gene rearrangements; lymphoblastic leukemia; acute lymphoblastic ... See more keywords