Impact of endometrial carcinoma histotype on the prognostic value of the TCGA molecular subgroups
Sign Up to like & getrecommendations! Published in 2020 at "Archives of Gynecology and Obstetrics"
DOI: 10.1007/s00404-020-05542-1
Abstract: Background The Cancer Genome Atlas (TCGA) identified four prognostic subgroups of endometrial carcinoma: copy-number-low/p53-wild-type (p53wt), POLE-mutated/ultramutated (POLEmt), microsatellite-instability/hypermutated (MSI), and copy-number-high/p53-mutated (p53mt). However, it is still unclear if they may be integrated with the current… read more here.
Keywords: subgroup; carcinoma; non endometrioid; histotype ... See more keywords
Sex disparities in head & neck cancer driver genes: An analysis of the TCGA dataset.
Sign Up to like & getrecommendations! Published in 2020 at "Oral oncology"
DOI: 10.1016/j.oraloncology.2020.104614
Abstract: OBJECTIVES Survival in head and neck squamous cell carcinoma (HNSCC) has been associated with patient sex, typically with males experiencing poorer outcomes. It is unclear if this disparity is based in divergent tumor biology. We… read more here.
Keywords: analysis; sex; tcga; hpv positive ... See more keywords
Identification of prognosis-related genes in the tumor microenvironment of stomach adenocarcinoma by TCGA and GEO datasets
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DOI: 10.1042/bsr20200980
Abstract: Abstract Accumulating evidence has demonstrated that tumor microenvironment (TME) plays a crucial role in stomach adenocarcinoma (STAD) development, progression, prognosis and immunotherapeutic responses. How the genes in TME interact and behave is extremely crucial for… read more here.
Keywords: tcga geo; geo datasets; tumor microenvironment; tumor ... See more keywords
The prognostic and clinical value of p53 upregulated modulator of apoptosis expression in solid tumors: a meta-analysis and TCGA data review
Sign Up to like & getrecommendations! Published in 2022 at "Expert Review of Molecular Diagnostics"
DOI: 10.1080/14737159.2022.2125802
Abstract: ABSTRACT Background Previous studies have reported the prognostic value of p53 upregulated modulator of apoptosis (PUMA) in numerous human tumors, but the conclusions have not been consistent. Therefore, this meta-analysis and the Cancer Genome Atlas… read more here.
Keywords: solid tumors; expression; p53 upregulated; analysis ... See more keywords
ACE: A Workbench Using Evolutionary Genetic Algorithms for Analyzing Association in TCGA.
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DOI: 10.1158/0008-5472.can-18-1976
Abstract: Modern methods of acquiring molecular data have improved rapidly in recent years, making it easier for researchers to collect large volumes of information. However, this has increased the challenge of recognizing interesting patterns within the… read more here.
Keywords: workbench; ace; cancer; using evolutionary ... See more keywords
A Three-Gene Immune Signature Including IDO1, BIN1 and PLXNC1 Predicts Survival in Acute Myeloid Leukemia
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DOI: 10.1182/blood-2020-139665
Abstract: Introduction A large body of evidence has increasingly demonstrated that the immune tumor microenvironment (TME) critically contributes to acute myeloid leukemia (AML) development. However, current AML prognostic classifications only rely on leukemia cell-intrinsic alterations and… read more here.
Keywords: ido1; plxnc1; tcga; expression ... See more keywords
The Better Survival of MSI Subtype Is Associated With the Oxidative Stress Related Pathways in Gastric Cancer
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2020.01269
Abstract: Background: Gastric cancer (GC) is the third leading fatal cancer in the world and its incidence ranked second among all malignant tumors in China. The molecular classification of GC, proposed by the The Cancer Genome… read more here.
Keywords: msi; gastric cancer; analysis; msi subtype ... See more keywords
TCGA-My: A Systematic Repository for Systems Biology of Malaysian Colorectal Cancer
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DOI: 10.3390/life12060772
Abstract: Colorectal cancer (CRC) ranks second among the most commonly occurring cancers in Malaysia, and unfortunately, its pathobiology remains unknown. CRC pathobiology can be understood in detail with the implementation of omics technology that is able… read more here.
Keywords: crc; repository; colorectal cancer; tcga ... See more keywords
Identification of the potential therapeutic target gene UBE2C in human hepatocellular carcinoma: An investigation based on GEO and TCGA databases
Sign Up to like & getrecommendations! Published in 2019 at "Oncology Letters"
DOI: 10.3892/ol.2019.10232
Abstract: Hepatocellular carcinoma (HCC) ranks the third major cause of cancer-associated mortality globally. Numerous studies have attempted to elucidate the underlying mechanisms of HCC using various biomarkers. In the present study, two expression profiles datasets from… read more here.
Keywords: hepatocellular carcinoma; expression; tcga; cancer ... See more keywords