Articles with "tcl1" as a keyword



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Comparison of karyotyping, TCL1 fluorescence in situ hybridisation and TCL1 immunohistochemistry in T cell prolymphocytic leukaemia

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Published in 2017 at "Journal of Clinical Pathology"

DOI: 10.1136/jclinpath-2017-204616

Abstract: Aims T cell prolymphocytic leukaemia (T-PLL) is defined as an aggressive T cell leukaemia composed of small to medium-sized lymphocytes with a mature T cell immunophenotype. Most of these cases are known to be associated… read more here.

Keywords: tcl1 rearrangement; prolymphocytic leukaemia; tcl1; cell prolymphocytic ... See more keywords
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Abstract 2566: A TCL1-specific T-cell receptor redirects T cells against B-cell lymphomas and non-hematological tumors

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Published in 2018 at "Immunology"

DOI: 10.1158/1538-7445.am2018-2566

Abstract: T-cell leukemia/lymphoma Antigen1 (TCL1) is a B-cell oncoprotein that is overexpressed in multiple forms of B-cell lymphoma. In our previous study, we identified a HLA*A0201-restricted T cell epitope from TCL1 that stimulated CD8+ T cells… read more here.

Keywords: tcl1; cell lymphomas; specific cell; cell receptor ... See more keywords
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Meta-Analysis Reveals Significant Sex Differences in Chronic Lymphocytic Leukemia Progression in the Eµ-TCL1 Transgenic Mouse Model

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Published in 2020 at "Cancers"

DOI: 10.3390/cancers12071980

Abstract: The Eµ-TCL1 transgenic mouse model represents the most widely and extensively used animal model for chronic lymphocytic leukemia (CLL). In this report, we performed a meta-analysis of leukemia progression in over 300 individual Eµ-TCL1 transgenic… read more here.

Keywords: leukemia; mouse model; tcl1 transgenic; tcl1 ... See more keywords