A TCR-Dependent Tissue Repair Potential of MAIT Cells.
Sign Up to like & getrecommendations! Published in 2019 at "Trends in immunology"
DOI: 10.1016/j.it.2019.09.001
Abstract: Three studies published in Cell Reports (Hinks et al., Lamichhane et al., and Leng et al.) describe the transcriptome of human and mouse mucosal-associated invariant T (MAIT) cells after cognate and noncognate stimulation. The results confirm the variability… read more here.
Keywords: mait cells; tcr dependent; tissue repair; mait ... See more keywords
Modulation of TCR-dependent NFAT signaling is impaired in HIV-1 Nef isolates from elite controllers.
Sign Up to like & getrecommendations! Published in 2019 at "Virology"
DOI: 10.1016/j.virol.2019.02.008
Abstract: HIV-1 Nef modulates the activation state of CD4+ T cells by altering signaling events elicited by the T cell receptor (TCR). Primary nef sequences exhibit extensive inter-individual diversity that influences their ability to downregulate CD4… read more here.
Keywords: hiv; nfat signaling; elite controllers; hiv nef ... See more keywords