Gene-enhancer variants reveal diverse TCR-mediated differentiation
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DOI: 10.1038/ni.3729
Abstract: The transcription factor IRF4 acts as a 'rheostat' for TCR signaling. Discrete levels of IRF4 can activate distinct transcriptional programs in T cells due to binding sites of variable affinity in groups of target genes. read more here.
Keywords: gene enhancer; tcr mediated; diverse tcr; enhancer variants ... See more keywords