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   Articles with "tcr repertoires" as a keyword



Dynamics of The Γδtcr Repertoires During The Dedifferentiation Process and Pilot Implications for Immunotherapy of Thyroid Cancer

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recommendations! Published in 2024 at "Advanced Science"

DOI: 10.1002/advs.202306364

Abstract: γδ T cells are evolutionarily conserved T lymphocytes that manifest unique antitumor efficacy independent of tumor mutation burden (TMB) and conventional human leukocyte antigen (HLA) recognition. However, the dynamic changes in their T cell receptor… read more here.

Keywords: cancer; repertoires dedifferentiation; tcr repertoires; thyroid cancer ... See more keywords
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Tools for fundamental analysis functions of TCR repertoires: a systematic comparison

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recommendations! Published in 2020 at "Briefings in Bioinformatics"

DOI: 10.1093/bib/bbz092

Abstract: Abstract The full set of T cell receptors (TCRs) in an individual is known as his or her TCR repertoire. Defining TCR repertoires under physiological conditions and in response to a disease or vaccine may… read more here.

Keywords: analysis; functions tcr; tcr repertoires; tcr repertoire ... See more keywords

High-throughput Sequencing Reveals that BCR and TCR Repertoires as Potential Prognostic Biomarkers for Pediatric Patients with B-ALL

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recommendations! Published in 2024 at "Current Genomics"

DOI: 10.2174/0113892029319425240813074610

Abstract: Background B-ALL is a hematologic malignancy that recurs in approximately 10-20% of children and has a poor prognosis. New prognostic biomarkers are needed to improve individualized therapy and achieve better clinical outcomes. Methods In this… read more here.

Keywords: high throughput; throughput sequencing; tcr repertoires; bcr tcr ... See more keywords

Exploration of shared features of B cell receptor and T cell receptor repertoires reveals distinct clonotype clusters

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recommendations! Published in 2022 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2022.1006136

Abstract: Although B cells and T cells are integral players of the adaptive immune system and act in co-dependent ways to orchestrate immune responses, existing methods to study the immune repertoire have largely focused on separate… read more here.

Keywords: cell receptor; receptor; tcr repertoires; bcr tcr ... See more keywords