The degree of prevalence of similarity between outer tropical cyclone rainbands and squall lines
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-26553-8
Abstract: Tropical cyclone rainbands (TCRs) are not only one of the most striking and persistent features of tropical cyclones (TCs) but also one of the major causes for extreme floods as TCs approach or encounter the… read more here.
Keywords: squall lines; similarity; cyclone rainbands; tropical cyclone ... See more keywords
Selection of highly responsive T cell receptors by an analysis combining the expression of multiple markers
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Science"
DOI: 10.1111/cas.15776
Abstract: The clinical success of T cell receptor (TCR) gene–transduced T (TCR‐T) cell therapy is expected as one of the next‐generation immunotherapies for cancer, in which the selection of TCRs with high functional avidity (high‐functional TCRs)… read more here.
Keywords: functional tcrs; cell; tcrs; expression ... See more keywords
Autoreactive T cell receptors with shared germline-like α chains in type 1 diabetes.
Sign Up to like & getrecommendations! Published in 2021 at "JCI insight"
DOI: 10.1172/jci.insight.151349
Abstract: Human islet antigen reactive CD4+ memory T cells (IAR T cells) play a key role in the pathogenesis of autoimmune type 1 diabetes (T1D). Using single-cell RNA sequencing (scRNA-Seq) to identify T cell receptors (TCRs)… read more here.
Keywords: iar cells; tcr junctions; type diabetes; tcrs ... See more keywords
Development of T-Cell Therapy Targeting Hematopoietic Minor Histocompatibility Antigen HA-1
Sign Up to like & getrecommendations! Published in 2019 at "Blood"
DOI: 10.1182/blood-2019-130552
Abstract: Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is currently the only curative therapy for hematological malignancies yet in nearly one-third of patients, it is followed by a relapse of the disease contributing to high mortality. In… read more here.
Keywords: minor histocompatibility; therapy; tcrs; cell ... See more keywords
PRAME and CTCFL-reactive TCRs for the treatment of ovarian cancer
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1121973
Abstract: Recurrent disease emerges in the majority of patients with ovarian cancer (OVCA). Adoptive T-cell therapies with T-cell receptors (TCRs) targeting tumor-associated antigens (TAAs) are considered promising solutions for less-immunogenic ‘cold’ ovarian tumors. In order to… read more here.
Keywords: cell; ovarian cancer; tcrs; prame ctcfl ... See more keywords
The Hypervariable Loops of Free TCRs Sample Multiple Distinct Metastable Conformations in Solution
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2018.00095
Abstract: CD4+ and CD8+ αβ T cell antigen recognition is determined by the interaction between the TCR Complementarity Determining Region (CDR) loops and the peptide-presenting MHC complex. These T cells are known for their ability to… read more here.
Keywords: hypervariable loops; free tcrs; solution; tcrs sample ... See more keywords
Needle in a Haystack: The Naïve Repertoire as a Source of T Cell Receptors for Adoptive Therapy with Engineered T Cells
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms21218324
Abstract: T cell engineering with antigen-specific T cell receptors (TCRs) has allowed the generation of increasingly specific, reliable, and versatile T cell products with near-physiological features. However, a broad applicability of TCR-based therapies in cancer is… read more here.
Keywords: needle haystack; cell receptors; repertoire; therapy ... See more keywords
The Influence of Traditional Cultural Resources (TCRs) on the Communication of Clothing Brands
Sign Up to like & getrecommendations! Published in 2020 at "Sustainability"
DOI: 10.3390/su12062379
Abstract: Recently, traditional cultural resources (TCRs) have become a core part of enterprise clothing branding strategies. Such clothes, expressed in traditional culture, are widely accepted and recognized by audiences. Unfortunately, industry has leveraged these brands poorly… read more here.
Keywords: clothing brands; communication; sign; traditional cultural ... See more keywords