Treacher Collins syndrome 3 (TCS3)-associated POLR1C mutants are localized in the lysosome and inhibits chondrogenic differentiation.
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DOI: 10.1016/j.bbrc.2018.03.136
Abstract: Treacher Collins syndrome (TCS) is a craniofacial developmental disorder whose key feature is a combination of symptoms. For example, a patient could have bilateral downward slanting of the palpebral fissures, colobomas of the lower eyelids,… read more here.
Keywords: tcs3 associated; collins syndrome; chondrogenic differentiation; differentiation ... See more keywords