Knockdown of translationally controlled tumor protein inhibits growth, migration and invasion of lung cancer cells
Sign Up to like & getrecommendations! Published in 2018 at "Life Sciences"
DOI: 10.1016/j.lfs.2017.09.039
Abstract: Aim: To investigate the role of translationally controlled tumor protein (TCTP) in lung cancer development. Main methods: A549 and HCC827 cells were transfected with shRNA specifically targeting TCTP mRNA. Cell growth was assessed by colony… read more here.
Keywords: migration invasion; tctp; lung cancer;
TCTP as a therapeutic target in melanoma treatment
Sign Up to like & getrecommendations! Published in 2017 at "British Journal of Cancer"
DOI: 10.1038/bjc.2017.230
Abstract: Background:Translationally controlled tumour protein (TCTP) is an antiapoptotic protein highly conserved through phylogeny. Translationally controlled tumour protein overexpression was detected in several tumour types. Silencing TCTP was shown to induce tumour reversion. There is a… read more here.
Keywords: melanoma; target melanoma; tctp; melanoma treatment ... See more keywords
Orchestration of myeloid-derived suppressor cells in the tumor microenvironment by ubiquitous cellular protein TCTP released by tumor cells.
Sign Up to like & getrecommendations! Published in 2021 at "Nature immunology"
DOI: 10.1038/s41590-021-00967-5
Abstract: One of most challenging issues in tumor immunology is a better understanding of the dynamics in the accumulation of myeloid-derived suppressor cells (MDSCs) in the tumor microenvironment (TIME), as this would lead to the development… read more here.
Keywords: suppressor cells; derived suppressor; tctp; myeloid derived ... See more keywords
Protein transduction domain of translationally controlled tumor protein: characterization and application in drug delivery
Sign Up to like & getrecommendations! Published in 2022 at "Drug Delivery"
DOI: 10.1080/10717544.2022.2122636
Abstract: Abstract Our research group reported in 2011 the discovery of a novel cell-penetrating moiety in the N-terminus of the human translationally controlled tumor protein (TCTP). This moiety was responsible for the previously noted membrane translocating… read more here.
Keywords: drug delivery; tctp; tctp ptd; protein ... See more keywords
Downregulation of transcription factor TCTP elevates microRNA-200a expression to restrain Myt1L expression, thereby improving neurobehavior and oxidative stress injury in cerebral palsy rats
Sign Up to like & getrecommendations! Published in 2020 at "Cell Cycle"
DOI: 10.1080/15384101.2020.1717044
Abstract: ABSTRACT Transcription factors have already been proposed to work on some human diseases. Yet the role of translationally controlled tumor protein (TCTP) in cerebral palsy (CP) remains elusive. This study intends to examine the mechanism… read more here.
Keywords: transcription; brain tissues; expression; factor ... See more keywords
Translationally controlled tumour protein (TCTP) from tomato and Nicotiana benthamiana is necessary for successful infection by a potyvirus.
Sign Up to like & getrecommendations! Published in 2017 at "Molecular plant pathology"
DOI: 10.1111/mpp.12426
Abstract: Translationally controlled tumour protein (TCTP) is a ubiquitously distributed protein in eukaryotes, involved in the regulation of several processes, including cell cycle progression, cell growth, stress protection, apoptosis and maintenance of genomic integrity. Its expression… read more here.
Keywords: protein; infection; benthamiana; tomato ... See more keywords
SAT0007 BLOCKING HISTAMINE-RELEASING FACTOR/TRANSLATIONALLY CONTROLLED TUMOR PROTEIN (HRF/TCTP) ATTENUATES AGGRESSIVENESS OF FIBROBLAST-LIKE SYNOVIOCYTES AND AMELIORATES COLLAGEN-INDUCED ARTHRITIS IN RHEUMATOID ARTHRITIS
Sign Up to like & getrecommendations! Published in 2020 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2020-eular.5088
Abstract: Background: Histamine-releasing factor/translationally controlled tumor protein (HRF/TCTP) stimulates cancer progression and allergic responses. Increased expression of HRF/TCTP occurs in joints of rheumatoid arthritis (RA) patients, but the role of HRF/TCTP in RA remains undefined Objectives:… read more here.
Keywords: hrf tctp; histamine releasing; arthritis; tctp ... See more keywords
Investigating the Role of Translationally Control Tumor Protein in Growth, Development and Differentiation of Dictyostelium discoideum
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2020.00742
Abstract: Translationally controlled tumor protein (TCTP) is a multifunctional protein implicated in various types of cellular processes involving growth and development of an organism. Here, we identified tctp gene in Dictyostelium discoideum and unraveled its function.… read more here.
Keywords: growth development; tumor protein; discoideum; development ... See more keywords
Long-Term Effect of Modified Glass Ionomer Cement with Mimicked Biological Property of Recombinant Translationally Controlled Protein
Sign Up to like & getrecommendations! Published in 2022 at "Polymers"
DOI: 10.3390/polym14163341
Abstract: This study modified glass ionomer cement (GIC) by adding mimicked biological molecules to reduce cell death. GIC was modified to BIOGIC by adding chitosan and bovine serum albumin for enhancing protein release. The BIOGIC was… read more here.
Keywords: tcp; mimicked biological; modified glass; tctp ... See more keywords