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BCG-induced trained immunity enhances acellular pertussis vaccination responses in an explorative randomized clinical trial

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Published in 2022 at "NPJ Vaccines"

DOI: 10.1038/s41541-022-00438-4

Abstract: Acellular pertussis (aP) booster vaccines are central to pertussis immunization programs, although their effectiveness varies. The Bacille Calmette-GuĂ©rin (BCG) vaccine is a prototype inducer of trained immunity, which enhances immune responses to subsequent infections or… read more here.

Keywords: pertussis; vaccination; trained immunity; bcg ... See more keywords