Chromatin Structure and the Pioneering Transcription Factor FOXA1 Regulate TDG-Mediated Removal of 5-Formylcytosine from DNA.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.9b07576
Abstract: Although a functional relationship between active DNA demethylation and chromatin structure is often implied, direct experimental evidence is lacking. We investigated the relationship between chromatin structure and thymine DNA glycosylase (TDG) using chemically defined nucleosome… read more here.
Keywords: chromatin structure; dna; tdg; chromatin ... See more keywords
Young stellar clumps in the interacting system Arp 305
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DOI: 10.1093/mnras/sty1017
Abstract: We present the results of optical long-slit spectral observations of interacting system Arp305 carried out at the 6m telescope BTA at the SAO RAS: the radial variation of gas kinematics and oxygen abundance. This study… read more here.
Keywords: galaxy; system; tdg; interacting system ... See more keywords
Abstract 1940: Thymine DNA glycosylase (TDG) as a novel target for melanoma
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DOI: 10.1158/1538-7445.am2018-1940
Abstract: Melanoma is an aggressive neoplasm with increasing incidence that bears the infamous distinction of being a recalcitrant cancer, i.e. a cancer with poor prognosis, lacking progress in diagnosis and treatment. In addition to conventional therapy,… read more here.
Keywords: melanoma; tdg; dna glycosylase; thymine dna ... See more keywords
Inducible TDG knockout models to study epigenetic regulation.
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DOI: 10.12688/f1000research.25637.1
Abstract: Mechanistic and functional studies by gene disruption or editing approaches often suffer from confounding effects like compensatory cellular adaptations generated by clonal selection. These issues become particularly relevant when studying factors directly involved in genetic… read more here.
Keywords: escs; dna; tdg; knockout models ... See more keywords