[Therapeutic drug monitoring in neuropsychopharmacology : Summary of the consensus guidelines 2017 of the TDM task force of the AGNP].
Sign Up to like & getrecommendations! Published in 2019 at "Der Nervenarzt"
DOI: 10.1007/s00115-018-0643-9
Abstract: Therapeutic drug monitoring (TDM) is the quantification and interpretation of drug concentrations in blood serum or plasma to optimize pharmacological therapy. TDM is an instrument with which the high interindividual variability of pharmacokinetics of patients… read more here.
Keywords: tdm task; drug; therapeutic drug; tdm ... See more keywords
The liposome of trehalose dimycolate extracted from M. bovis BCG induces antitumor immunity via the activation of dendritic cells and CD8+ T cells
Sign Up to like & getrecommendations! Published in 2021 at "Cancer Immunology, Immunotherapy"
DOI: 10.1007/s00262-021-02870-2
Abstract: Intravesical Bovis bacillus Calmette-Guérin (BCG) therapy is the most effective immunotherapy for bladder cancer, but it sometime causes serious side effects because of its inclusion of live bacteria. It is necessary to develop a more… read more here.
Keywords: lip tdm; trehalose dimycolate; tdm; bovis bcg ... See more keywords
Therapeutic Drug Monitoring in Pediatric Inflammatory Bowel Disease
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DOI: 10.1007/s11894-018-0623-z
Abstract: Purpose of reviewTherapeutic drug monitoring (TDM) has emerged as a useful tool to optimize the use of drug therapies in adults with inflammatory bowel disease (IBD), including both Crohn’s disease (CD) and ulcerative colitis (UC),… read more here.
Keywords: inflammatory bowel; disease; monitoring; tdm ... See more keywords
Reclassification des adénomes parathyroïdiens ectopiques par la TEMP-TDM : à propos de quatre cas
Sign Up to like & getrecommendations! Published in 2018 at "Annales d'Endocrinologie"
DOI: 10.1016/j.ando.2018.06.716
Abstract: Objectif Identifier l’origine superieure ou inferieure des adenomes parathyroidiens grâce a l’apport tridimensionnel de la tomographie par emission monophotonique (TEMP-TDM) afin de mieux guider le chirurgien. Methodes Nous rapportons les cas de quatre patients operes… read more here.
Keywords: des nomes; temp tdm; planaire; reclassification des ... See more keywords
Apport de la TEP/TDM dans les cancers broncho-pulmonaires non à petites cellules
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DOI: 10.1016/j.rmr.2016.10.187
Abstract: Introduction La tomographie par emission de positons couplee a la TDM est devenue un outil diagnostique de valeur dans le bilan d’extension et du suivi des cancers broncho-pulmonaires. Ces resultats peuvent conduire a une modification… read more here.
Keywords: broncho pulmonaires; cancers broncho; cas; tdm ... See more keywords
A FRET-Based Fluorogenic Trehalose Dimycolate Analogue for Probing Mycomembrane-Remodeling Enzymes of Mycobacteria
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DOI: 10.1021/acsomega.9b00130
Abstract: The mycobacterial outer membrane, or mycomembrane, is essential for the viability and virulence of Mycobacterium tuberculosis and related pathogens. The mycomembrane is a dynamic structure, whose chemical composition and biophysical properties can change during stress… read more here.
Keywords: mycomembrane remodeling; tdm; mycomembrane; activity ... See more keywords
Clinical Outcomes With Therapeutic Drug Monitoring in Inflammatory Bowel Disease: A Systematic Review With Meta-Analysis
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DOI: 10.1093/ecco-jcc/jjy109
Abstract: Background and Aims We undertook a systematic review and meta-analysis examining the effectiveness of therapeutic drug monitoring [TDM] to improve clinical outcomes in inflammatory bowel disease patients treated with anti-tumour necrosis factor alpha [anti-TNF] drugs.… read more here.
Keywords: reactive tdm; review meta; systematic review; drug ... See more keywords
A systematic review of the effect of therapeutic drug monitoring on patient health outcomes during treatment with penicillins
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DOI: 10.1093/jac/dkac101
Abstract: Abstract Background Dosing regimens guided by therapeutic drug monitoring (TDM) may be able to improve penicillin exposure in patients, which could result in improved patient health outcomes. Objectives This systematic review aims to describe the… read more here.
Keywords: penicillin; health; tdm; therapeutic drug ... See more keywords
Therapeutic drug monitoring for invasive mould infections and disease: pharmacokinetic and pharmacodynamic considerations
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DOI: 10.1093/jac/dkx029
Abstract: Therapeutic drug monitoring (TDM) may be required to achieve optimal clinical outcomes in the setting of significant pharmacokinetic variability, a situation that applies to a number of anti-mould therapies. The majority of patients receiving itraconazole… read more here.
Keywords: mould infections; drug; therapeutic drug; invasive mould ... See more keywords
Therapeutic drug monitoring in patients on biologics: lessons from gastroenterology.
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DOI: 10.1097/bor.0000000000000713
Abstract: PURPOSE OF REVIEW To give an overview on the role of therapeutic drug monitoring (TDM) of biologics in patients with inflammatory bowel disease (IBD). RECENT FINDINGS Numerous prospective exposure-response relationship studies and post-hoc analyses of… read more here.
Keywords: drug; gastroenterology; therapeutic drug; drug monitoring ... See more keywords
Limited Sampling Strategies Supporting Individualized Dose Adjustment of Intravenous Busulfan in Children and Young Adults.
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DOI: 10.1097/ftd.0000000000000700
Abstract: BACKGROUND AND AIMS Therapeutic drug monitoring (TDM) for busulfan supports dose adjustment during conditioning for stem cell transplantation. The authors aimed to develop and validate limited sampling strategies (LSS) of 4 to 5 samples for… read more here.
Keywords: sampling strategies; limited sampling; dose adjustment; busulfan ... See more keywords