Filling the gaps in peptide maps with a platform assay for top‐down characterization of purified protein samples
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DOI: 10.1002/pmic.202400036
Abstract: Liquid chromatography–mass spectrometry (LC‐MS) intact mass analysis and LC‐MS/MS peptide mapping are decisional assays for developing biological drugs and other commercial protein products. Certain PTM types, such as truncation and oxidation, increase the difficulty of… read more here.
Keywords: peptide maps; filling gaps; protein; tdms ... See more keywords